2012 & Earlier Publications

Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA. A novel monoclonal antibody to CD40 prolongs islet allograft survival. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2012; 12(8):2079-87. NIHMSID: NIHMS362878 PubMed [journal] PMID: 22845909, PMCID: PMC3410651

Adams AB, Newell KA. B cells in clinical transplantation tolerance. Seminars in immunology. 2012; 24(2):92-5. PubMed [journal] PMID: 21958959

Kitchens WH, Adams AB, Hughes CB, Subramanian RM. Diagnostic challenges in the evaluation of hepatic grafts from donors with HELLP syndrome: case report and review of the literature. Transplantation proceedings. 2011; 43(10):4010-2. PubMed [journal] PMID: 22172890

Turgeon NA, Avila JG, Cano JA, Hutchinson JJ, Badell IR, Page AJ, Adams AB, Sears MH, Bowen PH, Kirk AD, Pearson TC, Larsen CP. Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2010; 10(9):2082-91. NIHMSID: NIHMS337220 PubMed [journal] PMID: 20883542, PMCID: PMC3335736

Conrad MF, Adams AB, Guest JM, Paruchuri V, Brewster DC, LaMuraglia GM, Cambria RP. Secondary intervention after endovascular abdominal aortic aneurysm repair. Annals of surgery. 2009; 250(3):383-9. PubMed [journal] PMID: 19652592

Kean LS, Adams AB, Strobert E, Hendrix R, Gangappa S, Jones TR, Shirasugi N, Rigby MR, Hamby K, Jiang J, Bello H, Anderson D, Cardona K, Durham MM, Pearson TC, Larsen CP. Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2007; 7(2):320-35. PubMed [journal] PMID: 17241112

31.   Larsen CP, Knechtle SJ, Adams A, Pearson T, Kirk AD. A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2006; 6(5 Pt 1):876-83. PubMed [journal] PMID: 16611323

32.   Emmanouilidis N, Guo Z, Dong Y, Newton-West M, Adams AB, Lee ED, Wang J, Pearson  TC, Larsen CP, Newell KA. Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells. Transplantation. 2006; 81(3):455-62. PubMed [journal] PMID: 16477234

33.   Kean LS, Hamby K, Koehn B, Lee E, Coley S, Stempora L, Adams AB, Heiss E, Pearson TC, Larsen CP. NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation. American journal of transplantation : official journal of the American Society of Transplantation  and the American Society of Transplant Surgeons. 2006; 6(2):292-304. PubMed [journal] PMID: 16426313

34.   Larsen CP, Pearson TC, Adams AB, Tso P, Shirasugi N, Strobert E, Anderson D, Cowan S, Price K, Naemura J, Emswiler J, Greene J, Turk LA, Bajorath J, Townsend  R, Hagerty D, Linsley PS, Peach RJ. Rational development of LEA29Y (belatacept), 
a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2005; 5(3):443-53. PubMed [journal] PMID: 15707398

35.   Adams AB, Shirasugi N, Jones TR, Durham MM, Strobert EA, Cowan S, Rees P, Hendrix R, Price K, Kenyon NS, Hagerty D, Townsend R, Hollenbaugh D, Pearson TC, Larsen CP. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. Journal of immunology (Baltimore, Md.: 1950). 2005; 174(1):542-50. PubMed [journal] PMID: 15611281

36.   Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Schur CD, Pawlick RL, Wang L, Coyle AJ, Larsen CP, Shapiro AM. Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. American journal of transplantation : official journal of the American  Society of Transplantation and the American Society of Transplant Surgeons. 2004; 4(4):526-36. PubMed [journal] PMID: 15023144

37.   Kean LS, Manci EA, Perry J, Balkan C, Coley S, Holtzclaw D, Adams AB, Larsen CP, Hsu LL, Archer DR. Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease. Blood. 2003; 102(13):4582-93. PubMed [journal] PMID:  12933586

38.   Jones TR, Shirasugi N, Adams AB, Pearson TC, Larsen CP. Intravital microscopy identifies selectins that regulate T cell traffic into allografts. The Journal of clinical investigation. 2003; 112(11):1714-23. PubMed [journal] PMID: 14660747, PMCID: PMC281648

39.   Jones TR, Adams AB, Shirasugi NJ, Bingaman AW, Durham MM, Pearson TC, Larsen CP.  Allogeneic parenchymal and hematopoietic tissues differ in their ability to induce deletion of donor-reactive T cells. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(12):1520-30. PubMed [journal] PMID: 14629282

40.   Adams AB, Pearson TC, Larsen CP. Heterologous immunity: an overlooked barrier to tolerance. Immunological reviews. 2003; 196:147-60. PubMed [journal] PMID: 14617203

41.   Guo Z, Wang J, Dong Y, Adams AB, Shirasugi N, Kim O, Hart J, Newton-West M, Pearson TC, Larsen CP, Newell KA. Long-term survival of intestinal allografts induced by costimulation blockade, busulfan and donor bone marrow infusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(9):1091-8. PubMed [journal] PMID: 12919088

42.   Adams AB, Shirasugi N, Jones TR, Williams MA, Durham MM, Ha J, Dong Y, Guo Z,Newell KA, Pearson TC, Larsen CP. Conventional immunosuppression is compatible with costimulation blockade-based, mixed chimerism tolerance induction. American
journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003;
3(7):895-901. PubMed [journal] PMID: 12814483

43.   Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ, Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R, Larsen CP. Heterologous immunity provides a potent barrier to transplantation tolerance. The Journal of clinical investigation. 2003; 111(12):1887-95. PubMed [journal] PMID: 12813024, PMCID: PMC161424

44.   Wang J, Guo Z, Dong Y, Kim O, Hart J, Adams A, Larsen CP, Mittler RS, Newell KA.  Role of 4-1BB in allograft rejection mediated by CD8+ T cells. American journal of transplantation : official journal of the American Society of Transplantation  and the American Society of Transplant Surgeons. 2003; 3(5):543-51. PubMed [journal] PMID: 12752310

45.   Williams MA, Adams AB, Walsh MB, Shirasugi N, Onami TM, Pearson TC, Ahmed R, Larsen CP. Primary and secondary immunocompetence in mixed allogeneic chimeras. Journal of immunology (Baltimore, Md. : 1950). 2003; 170(5):2382-9. PubMed [journal] PMID: 12594261

46.   Williams MA, Onami TM, Adams AB, Durham MM, Pearson TC, Ahmed R, Larsen CP. Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen. Journal of immunology (Baltimore, Md. : 1950). 2002; 169(10):5387-91. PubMed [journal] PMID: 12421910

47.   Shirasugi N, Adams AB, Durham MM, Lukacher AE, Xu H, Rees P, Cowan SR, Williams MA, Pearson TC, Larsen CP. Prevention of chronic rejection in murine cardiac allografts: a comparison of chimerism- and nonchimerism-inducing costimulation blockade-based tolerance induction regimens. Journal of immunology (Baltimore, Md. : 1950). 2002; 169(5):2677-84. PubMed [journal] PMID: 12193741

48.   Kean LS, Durham MM, Adams AB, Hsu LL, Perry JR, Dillehay D, Pearson TC, Waller
EK, Larsen CP, Archer DR. A cure for murine sickle cell disease through stable
mixed chimerism and tolerance induction after nonmyeloablative conditioning and
major histocompatibility complex-mismatched bone marrow transplantation. Blood.
2002; 99(5):1840-9. PubMed [journal] PMID: 11861303

49.   Costimulation Blockade and Tolerance Adams AB, Larsen CP, Pearson TC.
Current opinion in organ transplantation. 2002 March; 7(1):7-12. My Bibliography [journal] 

50.   Adams AB, Shirasugi N, Durham MM, Strobert E, Anderson D, Rees P, Cowan S, Xu H, 
Blinder Y, Cheung M, Hollenbaugh D, Kenyon NS, Pearson TC, Larsen CP. Calcineurin
inhibitor-free CD28 blockade-based protocol protects allogeneic islets in
nonhuman primates. Diabetes. 2002; 51(2):265-70. PubMed [journal] PMID: 11812731

51.   Jones TR, Ha J, Williams MA, Adams AB, Durham MM, Rees PA, Cowan SR, Pearson TC, 
Larsen CP. The role of the IL-2 pathway in costimulation blockade-resistant
rejection of allografts. Journal of immunology (Baltimore, Md. : 1950). 2002;
168(3):1123-30. PubMed [journal] PMID: 11801646

52.   Adams AB, Larsen CP, Pearson TC, Newell KA. The role of TNF receptor and TNF
superfamily molecules in organ transplantation. American journal of
transplantation : official journal of the American Society of Transplantation and
the American Society of Transplant Surgeons. 2002; 2(1):12-8. PubMed [journal]
PMID: 12095050

53.   Williams MA, Tan JT, Adams AB, Durham MM, Shirasugi N, Whitmire JK, Harrington
LE, Ahmed R, Pearson TC, Larsen CP. Characterization of virus-mediated inhibition
of mixed chimerism and allospecific tolerance. Journal of immunology (Baltimore, 
Md. : 1950). 2001; 167(9):4987-95. PubMed [journal] PMID: 11673506

54.   Adams AB, Durham MM, Kean L, Shirasugi N, Ha J, Williams MA, Rees PA, Cheung MC, 
Mittelstaedt S, Bingaman AW, Archer DR, Pearson TC, Waller EK, Larsen CP.
Costimulation blockade, busulfan, and bone marrow promote titratable
macrochimerism, induce transplantation tolerance, and correct genetic
hemoglobinopathies with minimal myelosuppression. Journal of immunology
(Baltimore, Md. : 1950). 2001; 167(2):1103-11. PubMed [journal] PMID: 11441122

55.   Adams AB, Pearson TC, Larsen CP. Conventional immunosuppression and
co-stimulation blockade. Philosophical transactions of the Royal Society of
London. Series B, Biological sciences. 2001; 356(1409):703-5. PubMed [journal]
PMID: 11375073, PMCID: PMC1088457

56.   Williams MA, Trambley J, Ha J, Adams AB, Durham MM, Rees P, Cowan SR, Pearson TC,
Larsen CP. Genetic characterization of strain differences in the ability to
mediate CD40/CD28-independent rejection of skin allografts. Journal of immunology
(Baltimore, Md. : 1950). 2000; 165(12):6849-57. PubMed [journal] PMID: 11120808

57.   Barney M, Call GB, McIlmoil CJ, Husein OF, Adams A, Balls AG, Oliveira GK, Miner
EC, Richards TA, Crawford BK, Heckmann RA, Bell JD, Judd AM. Stimulation by
interleukin-6 and inhibition by tumor necrosis factor of cortisol release from
bovine adrenal zona fasciculata cells through their receptors. Endocrine. 2000;
13(3):369-77. PubMed [journal] PMID: 11216650

 Durham MM, Bingaman AW, Adams AB, Ha J, Waitze SY, Pearson TC, Larsen CP. Cutting
edge: administration of anti-CD40 ligand and donor bone marrow leads to
hemopoietic chimerism and donor-specific tolerance without cytoreductive
conditioning. Journal of immunology (Baltimore, Md. : 1950). 2000; 165(1):1-4.
PubMed [journal] PMID: 10861026

Call GB, Husein OF, McIlmoil CJ, Adams A, Heckmann RA, Judd AM. Bovine adrenal
cells secrete interleukin-6 and tumor necrosis factor in vitro. General and
comparative endocrinology. 2000; 118(2):249-61. PubMed [journal] PMID: 10890565

 Judd AM, Call GB, Barney M, McIlmoil CJ, Balls AG, Adams A, Oliveira GK. Possible
function of IL-6 and TNF as intraadrenal factors in the regulation of adrenal
steroid secretion. Annals of the New York Academy of Sciences. 2000; 917:628-37. 
PubMed [journal] PMID: 11268391

Gott JP, Thourani VH, Wright CE, Brown WM 3rd, Adams AB, Skardasis GM, McKinnon
WM, Battey PM, Guyton RA. Risk neutralization in cardiac operations: detection
and treatment of associated carotid disease. The Annals of thoracic surgery.
1999; 68(3):850-6; discussion 856-7. PubMed [journal] PMID: 10509973

Thourani VH, Feliciano DV, Cooper WA, Brady KM, Adams AB, Rozycki GS, Symbas PN. 
Penetrating cardiac trauma at an urban trauma center: a 22-year perspective. The American surgeon. 1999; 65(9):811-6; discussion 817-8. PubMed [journal] PMID: 10484082

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