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Publications 2015-2024
Adams, A. B., Blumberg, E. A., Gill, J. S., Katz, E., Kawai, T., Schold, J. D., Sykes, M., Tector, A., Sachs, D. H. (2024). Enhancing Kidney Transplantation and the Role of Xenografts: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. American journal of kidney diseases : the official journal of the National Kidney Foundation, 84(1), 94-101. PMID: 38452918 doi: 10.1053/j.ajkd.2023.12.025 |
Adams, A. B., Faber, D., Lovasik, B. P., Matar, A. J., Kim, S. C., Burlak, C., Tector, M., Tector, A. J. (2024). Iscalimab Combined With Transient Tesidolumab Prolongs Survival in Pig-to-Rhesus Monkey Renal Xenografts. Xenotransplantation, 31(4), e12880. PMID: 39185772 doi: 10.1111/xen.12880 |
Khush, K. K., Bernat, J. L., Pierson, 3rd, R. N., Silverman, H. J., Parent, B., Glazier, A. K., Adams, A. B., Fishman, J. A., Gusmano, M., Hawthorne, W. J., Homan, M. E., Hurst, D. J., Latham, S., Park, C. G., Maschke, K. J., Mohiuddin, M. M., Montgomery, R. A., Odim, J., Pentz, R. D., Reichart, B., Savulescu, J., Wolpe, P. R., Wong, R. P., Fenton, K. N. (2024). Research opportunities and ethical considerations for heart and lung xenotransplantation research: A report from the National Heart, Lung, and Blood Institute workshop. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 24(6), 918-927. PMID: 38514013 PMCID: PMC11144553 doi: 10.1016/j.ajt.2024.03.015 |
Vock, D. M., Humphreville, V., Ramanathan, K. V., Adams, A. B., Lim, N., Nguyen, V. H., Wothe, J. K., Chinnakotla, S. (2024). The landscape of liver transplantation for patients with alcohol-associated liver disease in the United States. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. PMID: 38727598 doi: 10.1097/LVT.0000000000000394 |
Adams, A. B., Blumberg, E. A., Gill, J. S., Katz, E., T. K., Schold, J. D., M. S., A. T., Sachs, D. H. Enhancing Kidney Transplantation: The Role of Xenografts (Report from a Scientific Workshop Sponsored by the National Kidney Foundation). American Journal of Kidney Disease. |
Leishman, D. J., Oppler, S. H., Stone LLH, O'Brien, T. D., Ramachandran, S., Willenberg, B. J., Adams, A. B., Hering, B. J., Graham, M. L. (2024). Targeted mapping and utilization of the perihepatic surface for therapeutic beta cell replacement and retrieval in diabetic non-human primates. Frontiers in transplantation, 3, 1352777. PMID: 38993753 PMCID: PMC11235263 doi: 10.3389/frtra.2024.1352777 |
Bhavsar, N. A., Patzer, R. E., Taber, D. J., Ross-Driscoll, K., Deierhoi Reed, R., Caicedo-Ramirez, J. C., Gordon, E. J., Matsouaka, R. A., Rogers, U., Webster, W., Adams, A., Kirk, A. D., McElroy, L. M. (2023). Defining the Need for Causal Inference to Understand the Impact of Social Determinants of Health: A Primer on Behalf of the Consortium for the Holistic Assessment of Risk in Transplantation (CHART). Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 4(3), e337. PMID: 38144885 PMCID: PMC10735082 doi: 10.1097/AS9.0000000000000337 |
Adams, A., Cendales, L. C., Cooper DKC, Cozzi, E., Gill, J., Judd, E., Katz, E., Kirk, A. D., Fishman, J. A., Reese, P. P., Wall, A., Markmann, J. F. (2023). American Society of Transplant Surgeons-American Society of Transplantation report of FDA meeting on regulatory expectations for xenotransplantation products. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 23(9), 1290-1299. PMID: 37217005 doi: 10.1016/j.ajt.2023.05.010 |
Lovasik, B. P., Kim, S. C., Higginbotham, L., Wakwe, W., Mathews, D. V., Breeden, C., Farris, A. B., Larsen, C. P., Ford, M. L., Nadler, S., Adams, A. B. (2023). CD28-Selective Inhibition Prolongs Non-Human Primate Kidney Transplant Survival. bioRxiv : the preprint server for biology. PMID: 37205571 PMCID: PMC10187313 doi: 10.1101/2023.05.03.539333 |
| Tector, A. J., Adams, A. B., Tector, M. (2023). Current Status of Renal Xenotransplantation and Next Steps. Kidney360, 4(2), 278-284. PMID: 36821619 doi: 10.34067/KID.0007152021 |
| Arenson, M., Hogan, J., Xu, L., Lynch, R., Lee, Y. H., Choi, J. D., Sun, J., Adams, A., Patzer, R. E. (2022). Predicting Kidney Transplant Recipient Cohorts' 30-Day Rehospitalization Using Clinical Notes and Electronic Health Care Record Data. Kidney international reports, 8(3), 489-498. PMID: 36938078 PMCID: PMC10014371 doi: 10.1016/j.ekir.2022.12.006 |
Badell, I. R., Bray, R. A., Elbein, R., Chami, A. S., Easley, K. A., Pastan, S. O., Guasch, A., Gebel, H. M., Adams, A. B., Larsen, C. P. (2021). Belatacept in Kidney Transplant Recipients With Failed Allografts for the Prevention of Humoral Sensitization: A Pilot Randomized Controlled Trial. Transplantation, 105(12), e395-e396. PMID: 34818307 doi: 10.1097/TP.0000000000003852 |
Adams, A. B., Lovasik, B. P., Faber, D. A., Burlak, C., Breeden, C., Estrada, J. L., Reyes, L. M., Vianna, R. M., Tector, M. F., Tector, A. J. (2021). Anti-C5 Antibody Tesidolumab Reduces Early Antibody-mediated Rejection and Prolongs Survival in Renal Xenotransplantation. Annals of surgery, 274(3), 473-480. PMID: 34238812 doi: 10.1097/SLA.0000000000004996 |
Kirk, A. D., Adams, A. B., Durrbach, A., Ford, M. L., Hildeman, D. A., Larsen, C. P., Vincenti, F., Wojciechowski, D., Woodle, E. S. (2021). Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 21(5), 1691-1698. PMID: 33128812 doi: 10.1111/ajt.16386 |
Thapa, M., Tedesco, D., Gumber, S., Elrod, E. J., Han, J. H., Kitchens, W. H., Magliocca, J. F., Adams, A. B., Grakoui, A. (2020). Blockade of BAFF Reshapes the Hepatic B Cell Receptor Repertoire and Attenuates Autoantibody Production in Cholestatic Liver Disease. Journal of immunology (Baltimore, Md. : 1950), 204(12), 3117-3128. PMID: 32332110 PMCID: PMC7306885 doi: 10.4049/jimmunol.1900391 |
| Kim SC, Mathews DV, Breeden CP, Ladowski J, Martens G, Stephenson AC, Farris AB, Jenkins J, Strobert ES, Walters EM, Larsen CP, Tector M, Tector JA, Adams AB . Long-Term Survival of Pig-to-Rhesus Macaque Renal Xenografts is Dependent on CD4 T cell Depletion. American Journal of Transplantation. 2019 Mar 1. |
| Mac Q*, Mathews DV*, Kahla JA, Stoffers CM, Delmas OM, Holt BA, Adams AB, Kwong GA. Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity. Nature Biomedical Engineering. 2019 Feb 19. |
| Mathews DV, Dong Y, Higginbotham LB, Kim SC, Breeden CP, Stobert EA, Jenkins J, Tso JY, Larsen CP, Adams AB. CD122 signaling in CD8+ memory T cells drives costimulation-independent rejection. J Clinical Invest. 2018 Oct 1;128(10):4557-4572. Pubmed [journal] PMID: 30222140 |
| Dana Tedesco, Manoj Thapa, Chui-Yoke Chin, Yong Ge, Minghao Gong, Jing Li, Sanjeev Gumber, Patrick Speck, Elizabeth J. Elrod, Eileen M. Burd, William H. Kitchens, Joseph F. Magliocca, Andrew B. Adams, David S. Weiss, Mansour Mohamadzadeh, Arash Grakou. Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-cell Receptor-positive Cells and Pathogenesis of Cholestatic Liver Disease. Gastroenterology. 2018 Feb 15. pii: S0016-5085(18)30214-2. doi: 10.1053/j.gastro.2018.02.019. Pubmed [journal] PMID: 29454797 |
| Newell KA, Adams AB, Turka LA.Biomarkers of operational tolerance following kidney transplantation - The immune tolerance network studies of spontaneously tolerant kidney transplant recipients. Hum Immunol. 2018 Feb 12. pii: S0198-8859(18)30045-4. doi:10.1016/j.humimm.2018.02.007. Review. PMID: 29448053 |
| Kim SC, Wakwe W, Higginbotham LB, Mathews DV, Breeden CP, Stephenson AC, Jenkins J, Strobert E, Price K, Price L, Kuhn R, Wang H, Yamniuk A, Suchard S, Farris AB 3rd, Pearson TC, Larsen CP, Ford ML, Suri A, Nadler S, Adams AB. Fc-Silent Anti-CD154 Domain Antibody Effectively Prevents Nonhuman Primate Renal Allograft Rejection. Am J Transplant. 2017 May;17(5):1182-1192. Pubmed [journal] PMID: 28097811 |
| Newman KL, Lynch RJ, Adams AB, Zhang R, Pastan SO, Patzer RE. Hospitalization Among Individuals Waitlisted for Kidney Transplant. Transplantation. 2017 Jun 6. Pubmed [journal] PMID: 28590946 |
| Adams AB, Goldstein J, Garrett C, Zhang R, Patzer RE, Newell KA, Turgeon NA, Chami AS, Guasch A, Kirk AD, Pastan SO, Pearson TC, Larsen CP. Belatacept Combined with Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function. Am J Transplant. 2017 May 23. Pubmed [journal] PMID: 28544101 |
| Mathews DV, Wakwe WC, Kim SC, Lowe MC, Breeden C, Roberts ME, Farris AB, Strobert EA, Jenkins JB, Larsen CP, Ford ML, Townsend R, Adams AB. Belatacept Resistant Rejection is Associated with CD28+ Memory CD8 T cells. Am J Transplant. 2017 May 14. Pubmed [journal] PMID: 28502128 |
| Cortes-Cerisuelo M, Laurie SJ, Mathews DV, Winterberg PD, Larsen CP, Adams AB, Ford ML. Increased Pre-Transplant Frequency of CD28+ CD4+ TEM Predicts Belatacept-Resistant Rejection in Human Renal Transplant Recipients. Am J Transplant. 2017 May 14. Pubmed [journal] PMID: 28502091 |
| Kitchens WH, Dong Y, Mathews DV, Breeden CP, Strobert E, Fuentes ME, Larsen CP, Ford ML, Adams AB. Interruption of OX40L signaling prevents costimulation blockade-resistant allograft rejection. JCI Insight. 2017 Mar 9;2 Pubmed [journal] PMID: 28289708 |
| Kim SC, Wang J, Dong Y, Mathews DV, Albrecht JA, Breeden CP, Farris AB, Lukacher AE, Ford ML, Newell KA, Adams AB. Alloimmunity But Not Viral Immunity Promotes Allograft Loss in a Mouse Model of Polyomavirus-Associated Allograft Injury. Transplant Direct. 2017 May 12. Pubmed [journal] PMID: 28620645 |
| Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB. Waitlist Hospital Admissions Predict Resource Utilization and Survival After Renal Transplantation. Annals of surgery. 2016; 264(6):1168-1173. PubMed [journal] PMID: 26720436 |
| Tedesco D, Thapa M, Gumber S, Elrod EJ, Rahman K, Ibegbu CC, Magliocca JF, Adams AB, Anania F, Grakoui A. CD4+ Foxp3+ T cells promote aberrant IgG production and maintain CD8+ T cell suppression during chronic liver disease. Hepatology (Baltimore, Md.). 2016; PubMed [journal] PMID: 27774611 |
| Lynch RJ, Zhang R, Patzer RE, Larsen CP, Adams AB. First-Year Waitlist Hospitalization and Subsequent Waitlist and Transplant Outcome. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2016; PubMed [journal] PMID:27664797 |
| Adams AB, Ford ML, Larsen CP. Costimulation Blockade in Autoimmunity and Transplantation: The CD28 Pathway. Journal of immunology (Baltimore, Md. : 1950). 2016; 197(6):2045-50. PubMed [journal] PMID: 27591335 |
| Zheng HB, Watkins B, Tkachev V, Yu S, Tran D, Furlan S, Zeleski K, Singh K, Hamby K, Hotchkiss C, Lane J, Gumber S, Adams AB, Cendales L, Kirk AD, Kaur A, Blazar BR, Larsen CP, Kean LS. The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2016; PubMed [journal] PMID: 27500470 |
| Adams AB, Newell KA. Transplantation tolerance: Coming of age. Hepatology (Baltimore, Md.). 2016; 64(2):347-9. PubMed [journal] PMID: 26991323 |
| Burghuber CK, Kwun J, Page EJ, Manook M, Gibby AC, Leopardi FV, Song M, Farris AB 3rd, Hong JJ, Villinger F, Adams AB, Iwakoshi NN, Knechtle SJ. Antibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2016;16(6):1726-38. NIHMSID: NIHMS746514 PubMed [journal] PMID: 26705099, PMCID: PMC4874845 |
| Newman KL, Fedewa SA, Jacobson MH, Adams AB, Zhang R, Pastan SO, Patzer RE. Racial/Ethnic Differences in the Association Between Hospitalization and Kidney Transplantation Among Waitlisted End-Stage Renal Disease Patients.Transplantation. 2016; NIHMSID: NIHMS741032 PubMed [journal] PMID: 26845307, PMCID: PMC4972697 |
| Kitchens WH, Adams AB. Nonhuman primate models of transplant tolerance: closer to the holy grail. Current opinion in organ transplantation. 2016; 21(1):59-65. PubMed [journal] PMID: 26709576 |
| Higginbotham L, Ford ML, Newell KA, Adams AB. Preventing T cell rejection of pig xenografts. International journal of surgery (London, England). 2015; 23(Pt B):285-90. PubMed [journal] PMID: 26306770 |
| Estrada JL, Martens G, Li P, Adams A, Newell KA, Ford ML, Butler JR, Sidner R, Tector M, Tector J. Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes. Xenotransplantation. 2015; 22(3):194-202. NIHMSID: NIHMS665047 PubMed [journal] PMID: 25728481, PMCID: PMC4464961 |
| Higginbotham L, Mathews D, Breeden CA, Song M, Farris AB 3rd, Larsen CP, Ford ML, Lutz AJ, Tector M, Newell KA, Tector AJ, Adams AB. Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model. Xenotransplantation. 2015; 22(3):221-30. NIHMSID: NIHMS797220 PubMed [journal] PMID: 25847130, PMCID: PMC4930152 |
| Velazquez VM, Uebelhoer LS, Thapa M, Ibegbu CC, Courtney C, Bosinger SE, Magliocca JF, Adams AB, Kirk AD, Knechtle SJ, Kalman D, Suthar MS, Grakoui A.Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. Hepatology (Baltimore, Md.). 2015;61(3):843-56. NIHMSID: NIHMS638180 PubMed [journal] PMID: 25331524, PMCID: PMC4340762 |
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Publications 2014-Later
| Knechtle SJ, Adams AB. Belatacept: is there BENEFIT for liver transplantation too? American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2014;14(8):1717-8. PubMed [journal] PMID: 25041120 |
| Squires MH 3rd, Hanish SI, Fisher SB, Garrett C, Kooby DA, Sarmiento JM, Cardona K, Adams AB, Russell MC, Magliocca JF, Knechtle SJ, Staley CA 3rd, Maithel SK.Transplant versus resection for the management of hepatocellular carcinoma meeting Milan Criteria in the MELD exception era at a single institution in a UNOS region with short wait times. Journal of surgical oncology. 2014; 109(6):533-41. NIHMSID: NIHMS657601 PubMed [journal] PMID: 24347475, PMCID: PMC4321953 |
| Sullivan JA, Adams AB, Burlingham WJ. The emerging role of TH17 cells in organ transplantation. Transplantation. 2014; 97(5):483-9. PubMed [journal] PMID: 24212502 |
| Ford ML, Adams AB, Pearson TC. Targeting co-stimulatory pathways: transplantation and autoimmunity. Nature reviews. Nephrology. 2014; 10(1):14-24. NIHMSID: NIHMS574732 PubMed [journal] PMID: 24100403, PMCID: PMC4365450 |
| Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA. A novel monoclonal antibody to CD40 prolongs islet allograft survival. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2012; 12(8):2079-87. NIHMSID: NIHMS362878 PubMed [journal] PMID: 22845909, PMCID: PMC3410651 |
| Adams AB, Newell KA. B cells in clinical transplantation tolerance. Seminars in immunology. 2012; 24(2):92-5. PubMed [journal] PMID: 21958959 |
| Kitchens WH, Adams AB, Hughes CB, Subramanian RM. Diagnostic challenges in the evaluation of hepatic grafts from donors with HELLP syndrome: case report and review of the literature. Transplantation proceedings. 2011; 43(10):4010-2. PubMed [journal] PMID: 22172890 |
| Turgeon NA, Avila JG, Cano JA, Hutchinson JJ, Badell IR, Page AJ, Adams AB, Sears MH, Bowen PH, Kirk AD, Pearson TC, Larsen CP. Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2010; 10(9):2082-91. NIHMSID: NIHMS337220 PubMed [journal] PMID: 20883542, PMCID: PMC3335736 |
| Conrad MF, Adams AB, Guest JM, Paruchuri V, Brewster DC, LaMuraglia GM, Cambria RP. Secondary intervention after endovascular abdominal aortic aneurysm repair. Annals of surgery. 2009; 250(3):383-9. PubMed [journal] PMID: 19652592 |
| Kean LS, Adams AB, Strobert E, Hendrix R, Gangappa S, Jones TR, Shirasugi N, Rigby MR, Hamby K, Jiang J, Bello H, Anderson D, Cardona K, Durham MM, Pearson TC, Larsen CP. Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2007; 7(2):320-35. PubMed [journal] PMID: 17241112 |
| Larsen CP, Knechtle SJ, Adams A, Pearson T, Kirk AD. A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2006; 6(5 Pt 1):876-83. PubMed [journal] PMID: 16611323 |
| Emmanouilidis N, Guo Z, Dong Y, Newton-West M, Adams AB, Lee ED, Wang J, Pearson TC, Larsen CP, Newell KA. Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells. Transplantation. 2006; 81(3):455-62. PubMed [journal] PMID: 16477234 |
| Kean LS, Hamby K, Koehn B, Lee E, Coley S, Stempora L, Adams AB, Heiss E, Pearson TC, Larsen CP. NK cells mediate costimulation blockade-resistant rejection of allogeneic stem cells during nonmyeloablative transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2006; 6(2):292-304. PubMed [journal] PMID: 16426313 |
| Larsen CP, Pearson TC, Adams AB, Tso P, Shirasugi N, Strobert E, Anderson D, Cowan S, Price K, Naemura J, Emswiler J, Greene J, Turk LA, Bajorath J, Townsend R, Hagerty D, Linsley PS, Peach RJ. Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2005; 5(3):443-53. PubMed [journal] PMID: 15707398 |
| Adams AB, Shirasugi N, Jones TR, Durham MM, Strobert EA, Cowan S, Rees P, Hendrix R, Price K, Kenyon NS, Hagerty D, Townsend R, Hollenbaugh D, Pearson TC, Larsen CP. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. Journal of immunology (Baltimore, Md.: 1950). 2005; 174(1):542-50. PubMed [journal] PMID: 15611281 |
| Nanji SA, Hancock WW, Anderson CC, Adams AB, Luo B, Schur CD, Pawlick RL, Wang L, Coyle AJ, Larsen CP, Shapiro AM. Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2004; 4(4):526-36. PubMed [journal] PMID: 15023144 |
| Kean LS, Manci EA, Perry J, Balkan C, Coley S, Holtzclaw D, Adams AB, Larsen CP, Hsu LL, Archer DR. Chimerism and cure: hematologic and pathologic correction of murine sickle cell disease. Blood. 2003; 102(13):4582-93. PubMed [journal] PMID: 12933586 |
| Jones TR, Shirasugi N, Adams AB, Pearson TC, Larsen CP. Intravital microscopy identifies selectins that regulate T cell traffic into allografts. The Journal of clinical investigation. 2003; 112(11):1714-23. PubMed [journal] PMID: 14660747, PMCID: PMC281648 |
| Jones TR, Adams AB, Shirasugi NJ, Bingaman AW, Durham MM, Pearson TC, Larsen CP. Allogeneic parenchymal and hematopoietic tissues differ in their ability to induce deletion of donor-reactive T cells. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(12):1520-30. PubMed [journal] PMID: 14629282 |
| Adams AB, Pearson TC, Larsen CP. Heterologous immunity: an overlooked barrier to tolerance. Immunological reviews. 2003; 196:147-60. PubMed [journal] PMID: 14617203 |
| Guo Z, Wang J, Dong Y, Adams AB, Shirasugi N, Kim O, Hart J, Newton-West M, Pearson TC, Larsen CP, Newell KA. Long-term survival of intestinal allografts induced by costimulation blockade, busulfan and donor bone marrow infusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(9):1091-8. PubMed [journal] PMID: 12919088 |
| Adams AB, Shirasugi N, Jones TR, Williams MA, Durham MM, Ha J, Dong Y, Guo Z,Newell KA, Pearson TC, Larsen CP. Conventional immunosuppression is compatible with costimulation blockade-based, mixed chimerism tolerance induction. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(7):895-901. PubMed [journal] PMID: 12814483 |
| Adams AB, Williams MA, Jones TR, Shirasugi N, Durham MM, Kaech SM, Wherry EJ, Onami T, Lanier JG, Kokko KE, Pearson TC, Ahmed R, Larsen CP. Heterologous immunity provides a potent barrier to transplantation tolerance. The Journal of clinical investigation. 2003; 111(12):1887-95. PubMed [journal] PMID: 12813024, PMCID: PMC161424 |
| Wang J, Guo Z, Dong Y, Kim O, Hart J, Adams A, Larsen CP, Mittler RS, Newell KA. Role of 4-1BB in allograft rejection mediated by CD8+ T cells. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2003; 3(5):543-51. PubMed [journal] PMID: 12752310 |
| Williams MA, Adams AB, Walsh MB, Shirasugi N, Onami TM, Pearson TC, Ahmed R, Larsen CP. Primary and secondary immunocompetence in mixed allogeneic chimeras. Journal of immunology (Baltimore, Md. : 1950). 2003; 170(5):2382-9. PubMed [journal] PMID: 12594261 |
| Williams MA, Onami TM, Adams AB, Durham MM, Pearson TC, Ahmed R, Larsen CP. Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen. Journal of immunology (Baltimore, Md. : 1950). 2002; 169(10):5387-91. PubMed [journal] PMID: 12421910 |
| Shirasugi N, Adams AB, Durham MM, Lukacher AE, Xu H, Rees P, Cowan SR, Williams MA, Pearson TC, Larsen CP. Prevention of chronic rejection in murine cardiac allografts: a comparison of chimerism- and nonchimerism-inducing costimulation blockade-based tolerance induction regimens. Journal of immunology (Baltimore, Md. : 1950). 2002; 169(5):2677-84. PubMed [journal] PMID: 12193741 |
| Kean LS, Durham MM, Adams AB, Hsu LL, Perry JR, Dillehay D, Pearson TC, Waller EK, Larsen CP, Archer DR. A cure for murine sickle cell disease through stable mixed chimerism and tolerance induction after nonmyeloablative conditioning and major histocompatibility complex-mismatched bone marrow transplantation. Blood. 2002; 99(5):1840-9. PubMed [journal] PMID: 11861303 |
| Costimulation Blockade and Tolerance Adams AB, Larsen CP, Pearson TC. Current opinion in organ transplantation. 2002 March; 7(1):7-12. My Bibliography [journal] |
| Adams AB, Shirasugi N, Durham MM, Strobert E, Anderson D, Rees P, Cowan S, Xu H, Blinder Y, Cheung M, Hollenbaugh D, Kenyon NS, Pearson TC, Larsen CP. Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. Diabetes. 2002; 51(2):265-70. PubMed [journal] PMID: 11812731 |
| Jones TR, Ha J, Williams MA, Adams AB, Durham MM, Rees PA, Cowan SR, Pearson TC, Larsen CP. The role of the IL-2 pathway in costimulation blockade-resistant rejection of allografts. Journal of immunology (Baltimore, Md. : 1950). 2002; 168(3):1123-30. PubMed [journal] PMID: 11801646 |
| Adams AB, Larsen CP, Pearson TC, Newell KA. The role of TNF receptor and TNF superfamily molecules in organ transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2002; 2(1):12-8. PubMed [journal] PMID: 12095050 |
| Williams MA, Tan JT, Adams AB, Durham MM, Shirasugi N, Whitmire JK, Harrington LE, Ahmed R, Pearson TC, Larsen CP. Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance. Journal of immunology (Baltimore, Md. : 1950). 2001; 167(9):4987-95. PubMed [journal] PMID: 11673506 |
| Adams AB, Durham MM, Kean L, Shirasugi N, Ha J, Williams MA, Rees PA, Cheung MC, Mittelstaedt S, Bingaman AW, Archer DR, Pearson TC, Waller EK, Larsen CP. Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression. Journal of immunology (Baltimore, Md. : 1950). 2001; 167(2):1103-11. PubMed [journal] PMID: 11441122 |
| Adams AB, Pearson TC, Larsen CP. Conventional immunosuppression and co-stimulation blockade. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2001; 356(1409):703-5. PubMed [journal] PMID: 11375073, PMCID: PMC1088457 |
| Williams MA, Trambley J, Ha J, Adams AB, Durham MM, Rees P, Cowan SR, Pearson TC, Larsen CP. Genetic characterization of strain differences in the ability to mediate CD40/CD28-independent rejection of skin allografts. Journal of immunology (Baltimore, Md. : 1950). 2000; 165(12):6849-57. PubMed [journal] PMID: 11120808 |
| Barney M, Call GB, McIlmoil CJ, Husein OF, Adams A, Balls AG, Oliveira GK, Miner EC, Richards TA, Crawford BK, Heckmann RA, Bell JD, Judd AM. Stimulation by interleukin-6 and inhibition by tumor necrosis factor of cortisol release from bovine adrenal zona fasciculata cells through their receptors. Endocrine. 2000; 13(3):369-77. PubMed [journal] PMID: 11216650 |
| Durham MM, Bingaman AW, Adams AB, Ha J, Waitze SY, Pearson TC, Larsen CP. Cutting edge: administration of anti-CD40 ligand and donor bone marrow leads to hemopoietic chimerism and donor-specific tolerance without cytoreductive conditioning. Journal of immunology (Baltimore, Md. : 1950). 2000; 165(1):1-4. PubMed [journal] PMID: 10861026 |
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| Judd AM, Call GB, Barney M, McIlmoil CJ, Balls AG, Adams A, Oliveira GK. Possible function of IL-6 and TNF as intraadrenal factors in the regulation of adrenal steroid secretion. Annals of the New York Academy of Sciences. 2000; 917:628-37. PubMed [journal] PMID: 11268391 |
| Gott JP, Thourani VH, Wright CE, Brown WM 3rd, Adams AB, Skardasis GM, McKinnon WM, Battey PM, Guyton RA. Risk neutralization in cardiac operations: detection and treatment of associated carotid disease. The Annals of thoracic surgery. 1999; 68(3):850-6; discussion 856-7. PubMed [journal] PMID: 10509973 |
Thourani VH, Feliciano DV, Cooper WA, Brady KM, Adams AB, Rozycki GS, Symbas PN. |
